An underground market for unlicensed weight-loss medications is being driven by social media fitness personalities and vendors on communication apps, according to new investigations.
Retatrutide, which remains in clinical trials, is being advertised by social media influencers for its supposed weight-reducing effects. Viewers are urged to contact these profiles directly for source information, while also obtaining promotional offers.
Separately, a robust trade exists on messaging services, where groups with numerous of members share “before and after” images, injection guides and assertions of next-day UK delivery. Sellers market the substance there before directing buyers to WhatsApp for transactions.
Retatrutide is an experimental injection developed by American pharmaceutical company Eli Lilly. The treatment affects three intestinal hormones – glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide and pancreatic hormone. Preliminary studies suggest it could assist patients lose up to a quarter of their body weight. Nicknamed the “triple G”, the substance is being hailed digitally as the next Ozempic.
However, doctors and chemists have warned that the distribution of what remains an unapproved medication in the UK is worrisome and could lead to users administering substances of uncertain source.
Several professionals stated the popularity for the experimental drug could be linked to the increasing price of licensed slimming treatments such as Mounjaro.
Selling the unapproved drug on TikTok or Telegram is prohibited in the UK, as it is an unapproved drug that cannot be promoted or distributed for personal consumption under the Human Medicines Regulations 2012.
Some influencers try to circumvent the rules by referring to the drug as a “research chemical” or citing it as “not for human consumption”. Retatrutide is not a controlled substance, but advertising and supply can still breach pharmaceutical, marketing, and consumer regulations, potentially leading to penalties, legal action or prison.
According to TikTok, the platform has taken down problematic content and banned associated keywords and query recommendations. The company stated it was committed to maintaining the platform safe and investing in strengthening compliance measures.
Research also found communities with up to 9,000 members marketing the experimental drug using Telegram's built-in search feature, which operates like a public directory. Entering “retatrutide” immediately displays groups with numerous of members, populated with photos of weight loss, positive reviews and detailed guides for preparing or injecting at residence.
Within minutes of entering one group, a vendor posted WhatsApp details, where most transactions take place. The seller sent an instruction manual and promised delivery within 48 hours. When questioned whether the substance was genuine, one seller said: “You can’t be sure.” Another shared a image of a alleged testing documentation. None inquired about weight, medical conditions or past usage.
Within these groups, messages show dark colored parcels with Royal Mail labels, stating to include fresh supplies. One communication read: “It took eight of us to load them this morning.”
Customers can select between powder vials, prepared at residence with sterile water, or ready-to-use pens typically priced at 160 pounds for 20 milligrams. When asked how long a injector should be used, vendors give conflicting answers varying between a few weeks to “depends on your body”.
A spokesperson for the messaging service stated it regularly monitored harmful content on its platform including material that encouraged the “misuse of controlled medications”. The company noted that it eliminated “millions of pieces of harmful content each day”.
“Individuals are administering substances they can’t verify. Even if the research behind this drug is sound, these online versions may not contain what they claim,” said Jason Murphy, the head of pharmaceutical services at a pharmacy service.
Dr Crystal Wyllie of Asda Online Doctor connected the increase in demand to current price rises for authorized weight-loss drugs such as Mounjaro. “With costs rising, patients are using online platforms. But fake injections are extremely risky. You cannot know what’s contained or whether the environment they were made in was sterile,” she said.
Her team has already seen patients injured by personal administration from unconfirmed sources. “We recognize the disappointment, but buying from Telegram or communication platforms is gambling with your health,” said Wyllie. “These materials could be contaminated or incorrectly dosed.”
A representative from the pharmaceutical company stated retatrutide was in phase 3 clinical trials and had not been reviewed or authorized by any regulatory agency globally. “Consequently at this point no one can sell [it] for human use,” they said, noting that any item “misleadingly claiming itself as a company investigational substance not yet authorized … may expose users to potentially significant medical dangers”.